Who We Are

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Company Overview

Our Mission

We transform critical care medicine by developing innovative and effective therapies based on alkaline phosphatase (RESCAP®). We are guided by our core values of loyalty towards relationships, accuracy, and high scientific commitment, which underpin everything we do. Our goal is to create a positive impact on the world by bringing new hope to patients and their families through safe, effective, and accessible treatments that improve outcomes and enhance quality of life.

Our Vision

Revolutionize critical care medicine through RESCAP®. We envision a world where RESCAP® improves patient outcomes, reduces mortality, and enhances quality of life. We are committed to scientific excellence, ethical standards, and building lasting relationships with patients, healthcare professionals, regulators, and investors.

Our Strategy

Alloksys’ strategy is to develop RESCAP® as a transformative therapy in critical care medicine. We will achieve this by conducting rigorous research and development, building strong relationships with key stakeholders, and maintaining the highest ethical and scientific standards. We will seek regulatory approval for RESCAP® in indications with high unmet medical need and significant market potential, prioritizing those where RESCAP® has demonstrated the most promising results. We will also explore new indications and production methods for RESCAP®, leveraging our scientific expertise and innovation capabilities.

Our Story

It all began with a strong belief in the potential of RESCAP® to revolutionize healthcare.

Exploratory Stage

Discovery of functionality of AP as an enzyme that detoxifies LPS.

Establishment and Merger Stage

Founding of PharmaAware and its merger with AMPharma to AMPHolding.

Foundational Expansion Stage

Founding of ALLOKSYS Life Sciences BV and start of the APPIRED 1 clinical study with RESCAP® in critical care.

Early Clinical Trials Stage

Continuation of APPIRED 1, start and completion of APPIRED1b and APPIRED2 clinical studies with RESCAP® in critical care, and start of the REUMAP pilot study with RESCAP® in rheumatoid arthritis.

Development and Foundational Evolution Stage

Completion of REUMAP pilot study, development of Recombinant human RESCAP, and founding of AMRIF BV.

Advanced Clinical Trials Stage

Phase 1 clinical study / pharmaco kinetics study of hRESCAP, start of APHIRI clinical study with RESCAP® in kidney transplantation, and start of APPIRED 3 clinical study with RESCAP® in critical care.

Clinical Expansion and COVID Research Stage

Continuation of APPIRED 3 and APHIRI clinical studies, start of MAP4B clinical study with RESCAP® in burn wounds, and start and completion of a COVID study.

Current Research and Development Stage

Interim results of APPIRED 3 study, start of APhIRI 2 study in kidney transplantation, and continuation of MAP4B and APPIRED 3 studies.

Our Team

The Alloksys team is committed to bringing RESCAP® to market and making it widely available for those who could benefit from it.

Leadership Team

Ruud Brands, PhD


Herman Feil, PhD


Willem Seinen, Prof., PhD


Ronald ppt

Ronald Oosting, PhD

Scientific Director

Hiskias ppt

Hiskias Keizer, PhD

Scientific Director

Marleen Vaes


ProQR_Wen An Liem

Dr. Wen Liem


Supervisory Board

Ton Bolier, MD

Bert Tournois, PhD

Frans van Duikeren

Daan van den Noort MD

Manohar Nandiraju

Scientific Board

Manuel Carrondo, Prof.

Dr. Jaqcues Schönenberger, MD

Dr. Anthony Hammond

Our Values

1. Scientific Excellence:
We are committed to rigorous scientific research and development to generate strong clinical evidence of the safety and efficacy of our therapies. We strive for scientific excellence in all our activities, from preclinical research to clinical trials and beyond.

2. Patient-Centered:
Patients and their families are at the center of everything we do. We are committed to developing therapies that meet their needs and improve their quality of life. We listen to their voices and engage with them in a meaningful way throughout the drug development process.

3. Collaboration:
We believe that successful drug development requires collaboration across disciplines, organizations, and geographies. We work closely with our partners, stakeholders, and regulators to ensure that our therapies are safe, effective, and accessible.

4. Ethics and Integrity:
We maintain the highest ethical and professional standards in all our activities, from scientific research to business operations. We operate with transparency, honesty, and integrity, putting the interests of patients and stakeholders first.

5. Innovation:
We embrace innovation and creativity in all aspects of our work. We strive to be at the forefront of scientific discovery and to bring novel therapies to patients in need. We continuously challenge ourselves to think outside the box and to find new solutions to unmet medical needs.

Our Partnerships

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